Successful Treatment with a Combination of Electrocautery Using Wire Snares and Gefitinib in Patients with EGFR-mutant Lung Cancer and Central Airway Obstruction
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概要
- 論文の詳細を見る
One-third of lung cancer patients present with life-threatening central airway obstruction (CAO). Two elderly patients were referred to our institution with symptoms caused by CAO. In each case, thoracic computed tomography and a bronchoscopic examination revealed a tumor obstructing the central airway. The tumors were resected endoscopically, and the patients' respiratory and performance status remarkably improved. Both patients were diagnosed with an advanced stage of lung adenocarcinoma harboring epidermal growth factor receptor (EGFR) mutations. They received gefitinib monotherapy, with partial responses sustained for more than 12 months. Combination therapy with endoscopic tumor resection and gefitinib is beneficial in patients with EGFR-mutant lung cancer and CAO.
- 社団法人 日本内科学会の論文
著者
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Demura Yoshiki
Department Of Respiratory Medicine University Of Fukui
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Matsuoka Hiroki
Department Of Biochemistry And Molecular Biology Nippon Medical School
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NISHI Koichi
Department of Biotechnology, Tottori University
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Kasahara Kazuo
Department Of Pulmonary Medicine Kanazawa City Hospital
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Matsuoka Hiroki
Department of Respiratory Medicine, Ishikawa Prefectural Central Hospital, Japan
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Araya Tomoyuki
Department of Respiratory Medicine, Ishikawa Prefectural Central Hospital, Japan
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Nishitsuji Masaru
Department of Respiratory Medicine, Ishikawa Prefectural Central Hospital, Japan
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Kasahara Kazuo
Department of Respiratory Medicine, Cellular Transplantation Biology, Kanazawa University Graduate School of Medical Science, Japan
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