Molecular basis of muscle hypertrophy and atrophy: Potential therapy for muscular dystrophy
スポンサーリンク
概要
- 論文の詳細を見る
Skeletal muscle mass is regulated by a balance of protein synthesis and degradation. The regulation of this protein synthesis/degradation system is linked with muscle activity, and leads to muscle hypertrophy/atrophy. However, recent studies suggested that this system is also linked to the mechanisms underlying muscular dystrophy. In this review, we summarize the recent advances relating to the molecular mechanisms of the protein synthesis/degradation system, and overview the new therapeutic strategy for muscular dystrophy that targets the molecular events that regulate muscle hypertrophy/atrophy.
- The Japanese Society of Physical Fitness and Sports Medicineの論文
著者
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Ito Naoki
Department Of Applied Chemistry Faculty Of Engineering Kyushu University
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TAKEDA Shin'ichi
Department of Molecular Therapy, National Institute of Neuroscience, National Center of Neurology and Psychiatry
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Miyagoe-Suzuki Yuko
Department of Molecular Therapy, National Institute of Neuroscience, National Center of Neurology and Psychiatry
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Ito Naoki
Department of Molecular Therapy, National Institute of Neuroscience, National Center of Neurology and Psychiatry
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- Molecular basis of muscle hypertrophy and atrophy: Potential therapy for muscular dystrophy
- Molecular basis of muscle hypertrophy and atrophy : Potential therapy for muscular dystrophy