Double-Blind, Placebo-Controlled, Randomized Phase II Study of TJ-14 (Hangeshashinto) for Infusional Fluorinated-Pyrimidine-based Colorectal Cancer Chemotherapy-induced Oral Mucositis
スポンサーリンク
概要
- 論文の詳細を見る
In the present study, the efficacy of TJ-14 for the prevention and/or treatment of chemotherapy induced oral mucositis is investigated in a randomized double-blind, placebo-controlled experimental clinical trial in colorectal cancer patients. The primary endpoint of this study is the incidence of persisting≧grade 2 oral mucositis, which is compared between the TJ-14 and placebo groups. The secondary endpoints include the duration of grade≧2 oral mucositis, and the worst oral mucositis grade throughout the protocol therapy, and time to disappearance of oral mucositis. Ninety patients are reqired in the study.
著者
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Kataoka Masato
Department Of Surgery Kyoto City Hospital
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Matsuda Chu
Department Of Surgery Osaka General Medical Center
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Munemoto Yoshinori
Department Of Gastroenterological Surgery Fukuiken Saiseikai Hospital
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MORITA Satoshi
Department of Biostastics and Epidemiology, Yokohama City University Medical Center
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Sakamoto Junichi
Tokai Central Hospital
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Mishima Hideyuki
Division Cancer Center of Aichi Medical College
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Kono Toru
Advanced Surgery Center Sapporo Higashi Tokushukai Hospital
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Nagata Naoki
Kitakyushu General Hospital
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Oshiro Mitsuru
Toho University Sakura Medical Center
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