Octaphlorethol A Inhibits the CpG-Induced Inflammatory Response by Attenuating the Mitogen-Activated Protein Kinase and NF-κB Pathways
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概要
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Octaphlorethol A is a phenolic compound isolated from the marine alga Ishige foliacea. In the present study, we investigated the anti-inflammatory activity of octaphlorethol A in CpG-stimulated primary murine bone marrow-derived macrophages and dendritic cells. It exhibited anti-inflammatory activity by regulating the mitogen-activated protein kinase and NF-κB pathways.
著者
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Kang Hee-Kyoung
School of Medicine, Institute of Medical Sciences, Cheju National University
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Yoo Eun-Sook
School of Medicine, Institute of Medical Sciences, Jeju National University
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Mathema Vivek
School of Medicine and Brain Korea 21 Program, Jeju National Universit
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Chae Doobyeong
School of Medicine, Brain Korea 21 Program, and Institute of Medical Science, Jeju National University
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Koh Young-Sang
School of Medicine and Brain Korea 21 Program, Jeju National Universit
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JEON You-Jin
Aqua Green Technology Co., 209 Jeju Bio-Industry Center
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MATHEMA Vivek
School of Medicine, Jeju National University
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MANZOOR Zahid
School of Medicine, Jeju National University
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YOO Eun-Sook
School of Medicine, Jeju National University
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CHAE Doobyeong
School of Medicine, Jeju National University
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- Octaphlorethol A Inhibits the CpG-Induced Inflammatory Response by Attenuating the Mitogen-Activated Protein Kinase and NF-κB Pathways