Serum lipoprotein (a) level in primary gout:Lipoprotein (a), an additional risk factor for atherosclerosis in gouty patients ?

概要

論文の詳細を見る
We measured the concentration ofserum lipoprotein(a)[Lp(a)], lipids, high density lipoprotein cholesterol (HDL-C) and apolipoprotein B (apo B) in patients with primary gout and control subjects.<BR>The serum concentrations of Lp (a), triglyceride and apo B were significantly higher (p<0.01) in the patients with primary gout than those in the control subjects, while the concentration of HDL-C was significantly lower (p<0.01) in the former than in the latter. No association was noted among Lp (a) concentration, and age, alcohol intake, body mass index, serum lipids, apo B and HDL-C concentrations in the patients with primary gout or in the control subjects.<BR>These findings suggest that an increase in Lp (a) concentration contributes to the development of atherosclerosis in primary gout in addition to a low level of HDL-C and a high level of apo B.