Estimations of Serum Uric Acid Levels in Public School Teachers

概要

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We studied serum uric acid levels in association with the clinical complications in human dock examinees which consist of 3056 public school teachers (2020 males and 1036 females). The following results were obtained. 1. Mean±SD in serum uric acid concentration were 5.54±1.25mg/dl for males and 4.38±0.97 mg/dl for females. It was regular distribution in females, but there was tendency to deviate toward higher levels in males. 2. There were no significant differences in serum uric acid levels from age 30 to 69 in both sexes. But, serum uric acid levels in females increased after menopause. 3. Serum uric acid value increased in proportion to the degree in their body weight. 4. The frequency of gouty attack in the past history was 2.1%(43/2020) for males and 0.5% (5/1036) for females. 5. The frequency of hyperuricemia was 5.8% (60/1036) for females (serum uric acid value>6 mg/dl) and 12.7% (257/2020)(U. A.>7 mg/dl) or 4.0% (81/2020) for males (U. A.>8 mg/dl). 6. There were no significant differences in dose of drinking alcohol between normal group and hyperuricemia group. 7. The proportion of obesity in hyperuricemia group was more than that in normal group. 8. Hyperuricemia group showed much higher frequency of having associated complications such as hyperlipidemia, hypertension and renal dysfunction (serum creatinine>1.2 mg/dl)than normal group.
Japanese Society of Gout and Nucleic Acid Metabolismの論文