The Association between Hyperuricemia and the Prevalence of Ischemic Changes in Electrocardiogram

概要

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The association of the electrocardiographic ischemic heart changes and the various conditions which were considered to be the probable risk factors of this disease, was studied on 3,692male subjects who received general medical health checks in Fukuoka University Hospital. Among the listed ten items, excess daily alcohol intake more than 80 ml (540 ml of Japanese "Sake"), overweight more than 110%, abnormal glucose tolerance test including diabetic and borderline type, hypertriglyceridemia above 150 mg/dl, and hypertension (diastolic pressure above 90 mm Hg, and/or systolic pressure above 140 mm Hg) were proved to associate ischemic heart changes with significantly high incidence, the more the above factors of high grade, the higher the incidence of ischemic changes. The prevalence of ischemic heart changes in cases with hyperuricemia above 8.0 mg/dl was higher than those with normal serum uric acid levels (less than 7.0 mg/dl), although not significant. One of the cause of the high incidence of ischemic heart changes in hyperuricemic patients, was considered to be the complication of the other risk factors, because in the cases with hyperuricemia, complication of multiple risk factors of high grade was more frequent than in those with normal uric acid levels.