Azacitidine-Induced Pneumonitis in a Patient with Myelodysplastic Syndrome: First Case Report in Japan
スポンサーリンク
概要
- 論文の詳細を見る
A 74-year-old Japanese man with myelodysplastic syndrome (MDS) received chemotherapy with azacitidine. From the second day after starting the administration, he complained of fever, cough and shortness of breath. Chest roentgenography and computed tomography showed consolidations and ground-glass opacities. His symptoms grew from worse to life-threatening. We diagnosed him with azacitidine-induced pneumonitis and began administering corticosteroids. Thereafter, his symptoms and radiographic abnormalities improved. Azacitidine is a hypomethylating agent that improves the survival of MDS patients. Although this drug is commonly well tolerated and rarely causes severe lung injury, it is important to consider the potentially serious adverse effects of azacitidine-induced pneumonitis.
著者
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Tsuchiya Yutaka
Department Of Pediatrics Keio University School Of Medicine
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Yamashita Jun
Department Of Biotechnology Faculty Of Engineering Kyoto Sangyo University
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Iwasaki Takuya
Department Of Applied Chemistry Faculty Of Engineering Nagasaki University
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Hayashi Makoto
Depart. Of Bioteclnology Graduate School Of Eng. Osaka Univ.
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Kokubu Fumio
Department Of Respiratory Medicine Showa University Fujigaoka Hospital
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MORI Hiraku
Department of Hematology, Showa University Fujigaoka Hospital
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Tsuchiya Yutaka
Department of Respiratory Medicine, Showa University Fujigaoka Hospital, Japan
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Tazawa Sakiko
Department of Respiratory Medicine, Showa University Fujigaoka Hospital, Japan
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Tomita Shogo
Department of Respiratory Medicine, Showa University Fujigaoka Hospital, Japan
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Tateno Hidetsugu
Department of Respiratory Medicine, Showa University Fujigaoka Hospital, Japan
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Takayasu Hiromi
Department of Respiratory Medicine, Showa University Fujigaoka Hospital, Japan
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Tada Mami
Department of Respiratory Medicine, Showa University Fujigaoka Hospital, Japan
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Yamazaki Yohei
Department of Respiratory Medicine, Showa University Fujigaoka Hospital, Japan
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Wakabayashi Aya
Department of Respiratory Medicine, Showa University Fujigaoka Hospital, Japan
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Takeda Norikazu
Department of Respiratory Medicine, Showa University Fujigaoka Hospital, Japan
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