Epstein-Barr virus-Associated Meningitis Presenting with Hearing Impairment
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概要
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A 42-year-old man presented with fever, headache and liver dysfunction, and was diagnosed as having aseptic meningitis by lumbar puncture. The PCR detected Epstein-Barr virus (EBV)-DNA in the peripheral blood and cerebrospinal fluid. About 20 days after onset, the patient presented with hearing impairment in the right ear, which was confirmed by a pure tone audiogram. The hearing acuity improved after the initiation of hydrocortisone sodium phosphate. We presume that the hearing impairment was due to auditory nerve neuritis related to extension of inflammation of the meninges. This is the first reported case of EBV-associated meningitis showing hearing impairment.
著者
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MIYASHITA Tomoyuki
Department of Experimental Surgery and Bioengineering, National Children's Medical Research Center
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Ishihara Shoichiro
Department Of Neurology And Neurological Science Graduate School Tokyo Medical And Dental University
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Shintani Shuzo
Department Of Neurology Toride Kyodo General Hospital
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Kobayashi Zen
Department Of Neurology And Neurological Science Graduate School Tokyo Medical And Dental University
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Numasawa Yoshiyuki
Department Of Neurology Toride Kyodo General Hospital
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Akaza Miho
Department of Clinical and Molecular Endocrinology, Tokyo Medical and Dental University Graduate School
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Miyashita Tomoyuki
Department of Neurology, JA Toride Medical Center, Japan
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Ishihara Shoichiro
Department of Neurology, JA Toride Medical Center, Japan
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Shintani Shuzo
Department of Neurology, JA Toride Medical Center, Japan
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Numasawa Yoshiyuki
Department of Neurology, JA Toride Medical Center, Japan
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Numasawa Yoshiyuki
Department of Neurology and Neurological Science, Graduate School, Tokyo Medical and Dental University
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