A Case of an Elderly Patient with Slowly Progressive Type 1 Diabetes Who Developed Severe Nonocclusive Mesenteric Ischemia without Predisposing Events
スポンサーリンク
概要
- 論文の詳細を見る
A 72-year-old woman with slowly progressive type 1 diabetes (SPIDDM) was admitted to our hospital because of increasing abdominal pain and diarrhea. The patient was diagnosed with nonocclusive mesenteric ischemia (NOMI), and a subtotal colonectomy was performed successfully. The resected sample revealed transmural gangrenous necrosis of the colon and rectum. This case is interesting because the severe NOMI occurred in a SPIDDM patient without common predisposing events such as hypoperfusion. Prolonged generation of reactive oxygen species in SPIDDM, together with the decline in adaptive response to oxidative stress with aging, might be an exacerbating factor for ischemic injury in the elderly.
著者
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Mori Hiroyuki
Department Of Biological Information Graduate School Of Bioscience And Biotechnology Tokyo Institute
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Akita Hozuka
Department Of General Internal Medicine Hyogo Prefecture Health Promotion Association
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Akisaki Taichi
Department Of Internal And Geriatric Medicine Kobe University Graduate School Of Medicine
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Yokono Koichi
Department Of General Internal Medicine Kobe University Graduate School Of Medicine
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Hara Kenta
Department Of Biological Science Graduate School Of Sciences Osaka University
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Arai Takashi
Department Of Applied Biological Science Faculty Of Science And Technology Science University Of Tok
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Yasuda Hisafumi
Department of General Internal Medicine, Kobe University Hospital, Japan
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Yokono Koichi
Department of General Internal Medicine, Kobe University Hospital, Japan
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Miyoshi Sonoko
Department of General Internal Medicine, Kobe University Hospital, Japan
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Kubokawa Osamu
Department of General Internal Medicine, Kobe University Hospital, Japan
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Kido Yoshiaki
Kobe University Graduate School of Health Sciences, Japan
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Hara Kenta
Department of General Internal Medicine, Kobe University Hospital, Japan
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Mori Hiroyuki
Department of General Internal Medicine, Kobe University Hospital, Japan
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MORI Hiroyuki
Department of Agricultural Chemistry, Kochi University
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Akita Hozuka
Department of General Internal Medicine, Kobe University Hospital, Japan
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