The Pathological Effect of Aberrant Artery to The Normal Lung Tissue in The Cases of Intralobar Pulmonary Sequestration.

概要

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Intralobar pulmonary sequestration (ILS) often has anastomoses of the aberrant artery (AA) to the pulmonary artery (PA). There are few investigations about the pathological effect caused by the AA to PA anastomoses. The purpose of our study is to examine the vascular lesions of the non sequestrated lungs; the rest area in the resected lobes besides the sequestrated lesion. Aortogram showed the anastomoses of AA to PA in 4 out of 9 patients, who were underwent lobectomy at National Children's Hospital. The blood flow from the AA extended to the PA in the adjacent lobe. Three of those who had anastomoses showed hypertrophic media of the PA, which were classified from grade 1 to grade 3 according to the Heath-Edwards classification. The rest of patients showed no pathological change of the PA. This study suggested that the hypertensive change of the PA closely related to the AA to PA anastomoses and the histories of infection might contribute to the hypertensive change of the PA.