The Levels of Amilase in Tracheobronchial Secretion in Infants and Children

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We investigated the levels of amylase activity in tracheobronchial secretion (LATBSs) in the infants and children with tracheostomy or those intubated for months (group A) and those intubated transiently (group B) to know the effect of aspiration of saliva on the LATBS.<BR>We detected amylase in all speciments of the secretion we investigated. The LATBSs were not correlated to the volume of the mucus aspirated from trachea or bronchus. There was no significant difference of the LATBSs between group A and group B. A girl who habitually developed massive intratracheal aspiration had significantly higher LATBSs than the whole data of the other patients. But her LATBSs were significantly lower than that of one infant who did not have massive aspiration. We got high LATBS in a specimen aspirated from a patient just after developing transient massive aspiration. It recovered to normal range after 5 days. Feeding of milk significantly increased the LATBSs in group A.<BR>We found some circadian rhythms in the LATBSs of patients in group A. These patterns of the circadian rhyshms appeared to be characteristic to each patient.