Quantitative analysis of effects of substituted phenols on membrane characteristics of lecithin liposomes.
スポンサーリンク
概要
- 論文の詳細を見る
The partition coefficient of a series of substituted phenols in a lecithin liposome/water system, <I>P</I>(L/W), and the effects of these compounds on the perturbation of liposomal membranes were quantitatively investigated using physicochemical molecular parameters. Partition behavior is primarily governed by hydrophobicity, represented in terms of the 1-octanol/water partition coefficient. Steric and electronic characters also were of significance. Potency in perturbation of liposomal membranes was governed by the degree of partitioning to the membrane and the steric bulkiness of the phenol. This kind of quantitative procedure was very helpful in investigating the effects of organic molecules on membrane characteristics.
- 公益社団法人 日本化学会の論文
著者
-
Miyoshi Hideto
Department Of Agricultural Chemistry Faculty Of Agriculture Kyoto University
-
Nishioka Takaaki
Departments Of Gastroenterology Matsusaka Chuo Hospital
-
Fujita Toshio
Department Of Agricultural Chemistry Kyoto University
-
Nishioka Takaaki
Department of Agricultural Chemistry, Faculty of Agriculture, Kyoto University
関連論文
- PE-295 Pioglitazone Remains Effective to Prevent Development of New Coronary Lesion in Diabetics at Medium Term : Results from Multicenter CHAMPION Trial(PE050,Diabetes 1 (H),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circ
- OE-368 Ligand-independent activation of angiotensin II type 1 receptor by mechanical stretch(Cardiac Hypertrophy, Basic and Clinical 1 (M) : OE46)(Oral Presentation (English))
- Quantitative Analysis of the Antimicrobial Activity and Membrane-perturbation Potencyof Antifouling Para-substituted Alkylphenols
- OE-340 Impact of Pioglitazone on Short-term Outcomes after Implantation of Sirolimus-Eluting Stents in Diabetics : Results from the CHAMPION Trial(Diabetes/Obesity/Metabolic syndrome(02)(H),Oral Presentation(English),The 72nd Annual Scientific Meeting of
- Colonic and peritoneal tuberculosis associated with coloduodenal fistula
- Uncoupling Mechanism of Glycoside Antibiotic Aculeximycin in Isolated Rat-Liver Mitochondria
- Uncoupling Action of Antibiotic Sporaviridins with Rat-liver Mitochondria
- SW-4 Relationship between Insecticidal Activity of Pyrethroids and their Neurophysiological Parameter Determined with Crayfish Giant Axons
- Increase of scavenger receptor A-positive monocytes in patients with acute coronary syndromes
- Direct Interaction between Mitochondrial Succinate-Ubiquinone and Ubiquinol-Cytochrome c Oxidoreductases Probed by Sensitivity to Quinone-Related Inhibitors
- Flower-Inducing Activity of Benzoic Acid Derivatives for Lemna minor
- Specific Interaction of Cytokinins and Their Analogs with Rotenone-sensitive Internal NADH Dehydrogenase in Potato Tuber Mitochondria
- Effects of Phenolic Respiration Inhibitors on Cytochrome bc1 Complex of Rat-liver Mitochondria
- Development of the Convenient and Direct Numerical Analytical Method of the Pharmacokinetics of Phenytoin by an Ordinary and/or the Bayesian Weighted Least-Squares Method Using the Program MULTI2 (BAYES)
- Relationship between Structure and Flower-inducing Activity of Benzoic Acid Derivatives in Lemna paucicostata 151
- Effects of Insect-Growth-Regulatory Benzimidazole Derivatives on Cultured Integument of the Rice Stem Borer and Mitochondria from Rat Liver
- Quantitative analysis of effects of substituted phenols on membrane characteristics of lecithin liposomes.
- Quantitative analysis of partition behavior of substituted phenols from aqueous phase into liposomes made of lecithin and various lipids.
- Cultured Integument of Chilo suppressalis as a Bioassay System for Juvenile Hormones
- Scavenger receptor A index and coronary thrombus in patients with acute ST elevation myocardial infarction
- Uncoupling Mechanism of Glycoside Antibiotic Aculeximycin in Isolated Rat-Liver Mitochondria.