Selective 1,4-chiral induction in the reaction of enolates generated from t-butyl .DELTA.-hydroxy carboxylates.
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概要
- 論文の詳細を見る
Lithium enolates generated from <I>t</I>-butyl esters of δ-hydroxy carboxylic acids with lithium dialkylamides in THF–HMPA were alkylated stereoselectively to give the corresponding <I>syn</I>-α-alkylated δ-hydroxy esters. The generation of the enolates was accelerated by the addition of lithium trifluoromethanesulfonate, and the successive aldol and hydroxylation reactions of the enolates also proceeded in a stereoselective manner.
- 公益社団法人 日本化学会の論文
著者
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Ukaji Yutaka
Department Of Chemical Science Graduate School Of Natural Science And Technology Kanazawa University
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Narasaka Koichi
Department Of Applied Chemistry Faculty Of Engineering Kyushu Institute Of Technology
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Watanabe Kazutoshi
Department of Chemistry, Faculty of Science, The University of Tokyo
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