The Dehydration of <I>N</I>-Benzyloxy and <I>N</I>-Hydroxymaleamic Acid and the Isomerization of <I>N</I>-Benzyloxyisomaleimide
スポンサーリンク
概要
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The dehydration of <I>N</I>-benzyloxy and <I>N</I>-hydroxymaleamic acids and the isomerization of <I>N</I>-benzyloxyisomaleimide were carried out under various conditions to obtain <I>N</I>-benzyloxyisomaleimide, <I>N</I>-hydroxyisomaleimide, and <I>N</I>-benzyloxymaleimide. <I>N</I>-substituents, such as benzyloxy, hydroxy, and acetoxy groups, depress the reactivity of nitrogen electronically and facilitate the formation of isomaleimides in the dehydration of <I>N</I>-substituted maleamic acids. The thermal isomerization of <I>N</I>-benzyloxyisomaleimide to the maleimide has been successful only in <I>N</I>,<I>N</I>-dimethylformamide. Further the conversion of isomaleimide to maleimide was performed <I>via</I> the addition of hydrogen bromide to isomaleimide followed by isomerization and dehydrobromination.
- 公益社団法人 日本化学会の論文
著者
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Okawara Makoto
Research Laboratory Of Resources Utilization Tokyo Institute Of Technology
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Akiyama Masayasu
Research Laboratory of Resources Utilization, Tokyo Institute of Technology
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Narita Mitsuaki
Research Laboratory of Resources Utilization, Tokyo Institute of Technology
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