A Novel Synthesis of L-Pipecolic Acid
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概要
- 論文の詳細を見る
A novel synthesis of L-pipecolic acid from L-lysine is described. Bromination of ε-NH<SUB>2</SUB> group on <I>N</I><SUP>α</SUP>-tosyl-L-lysine, followed by cyclization with NaH in DMF gave <I>N</I>-tosyl-L-pipecolic acid in 45% yield.
- 公益社団法人 日本化学会の論文
著者
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FUJII Toshiyuki
Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
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Miyoshi Muneji
Research Laboratory of Applied Biochemistry, Department of Synthetic Chemistry, Tanabe Seiyaku Co., Ltd.
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