RELATIONSHIP BETWEEN CNS DEPRESSANT ACTIVITY AND SELECTIVE ENZYME INHIBITION BY QUINAZOLONE SALICYLHYDRAZIDE DERIVATIVES
スポンサーリンク
概要
- 論文の詳細を見る
Substituted quinazolone salicylhydrazides exhibiting anticonvulsant activity against pentylenetetrazol and maximal electric shock (MES) seizures were found to potentiate nembutal induced hypnosis in mice. All these compounds were found to inhibit selectively in vitro oxidation of pyruvic acid and α-ketoglutaric acid. The relative electronegativity of the substituents at position 6 of the quinazolone nucleus in no way paralleled their enzyme inhibitory effects.
- 公益社団法人 日本薬理学会の論文
著者
-
Kumar R.
Department Of Microbiology And Microbial Technology School Of Biological Sciences Madurai Kamaraj Un
-
Gupta T.k.
Department Of Microbiology Research Divisioin East India Pharmaceutical Works Ltd
-
PARMAR Surendra
Department of Pharmacology & Therapeutics, King George's Medical College
-
ALI Basheer
Department of Pharmacology & Therapeutics, King George's Medical College
-
ALI Basheer
Department of Pharmacology & Therapeutics, King George's Medical College
関連論文
- PARAMETERIZATION OF WAVE ATTENUATION IN MUDDY BEDS AND IMPLICATION ON COASTAL STRUCTURES
- Bioconversion of Gallic Acid into Pyrogallol by Immobilized Citrobacter freundii TB3
- ROLE OF CATECHOLAMINES IN THE MEDIATION OF PERIPHERAL EFFECTS OF FEMALE SEX HORMONES
- ROLE OF CATECHOLAMINES IN THE CENTRAL ACTIONS OF FEMALE SEX HORMONES
- Mechanism of tricuspid regurgitation in corrected transposition of great arteries
- Aspergillus oryzaeの深部培養下アミラーゼ生産に対する培養および栄養条件の影響
- Plasma Insulin and Growth Hormone during Antarctic Residence
- TSUNAMI TRAVEL TIME COMPUTATION AND SKILL ASSESSMENT FOR THE 26 DECEMBER 2004 EVENT IN THE INDIAN OCEAN
- EFFECT OF SOME NEWER MONOAMINE OXIDASE INHIBITORS ON CATECHOLAMINE INDUCED PRESSOR RESPONSES
- PROTEIN AND MALT QUALITY IN SOME GAMMA-RAY INDUCED HIGH YIELDING MUTANTS IN BARLEY (HORDEUM VALGARE)
- ANTICONVULSANT PROPERTIES OF SOME NEWER MONOAMINE OXIDASE INHIBITORS
- ヘレーショウセル内の液/液分散流
- CORRELATION BETWEEN SELECTIVE INHIBITION OF NADDEPENDENT OXIDATIONS AND ANTICONVULSANT PROPERTY OF QUINAZOLONE ALLYLETHERS AND QUINAZOLONE ALLYLPHENOLS
- A STUDY OF ANTI-OVULATORY ACTIVITY OF HALOPERIDOL IN RABBITS
- Heat Transfer in Laminar Flow of Bingham Material through an Annulus
- EVIDENCE FOR NON-INVOLVEMENT OF CENTRAL CATECHOLAMINES IN COPPER ACETATE INDUCED OVULATION
- RELATIONSHIP BETWEEN CNS DEPRESSANT ACTIVITY AND SELECTIVE ENZYME INHIBITION BY QUINAZOLONE SALICYLHYDRAZIDE DERIVATIVES
- EVIDENCE FOR β-ADRENERGIC BLOCKING PROPERTY OF 1-ISOPROPYLAMINO-3-(β-NAPHTHOXY)-2-PROPANOL (β-PROPRANOLOL)