甲状腺機能亢進症に於ける皮膚色素の増加について

概要

論文の詳細を見る
Hyperpigmentation in patients with hyperthyroidism has been noted by many clinicians and according. to various papers and monographs, the frequency of hyperpigmentation ranged from 3 to 70% of the patients, but these results were obtained mainly either from the patient's history or from the subjective observation of the physicians and there has been no work in which the change of pigmentation in hyperthyroidism was measured objectively. <BR>In this report the degree of pigmentation of the abdominal skin in patients with hyperthyroidism has been measured by photoelectric reflection meter before and after thyroidectomy. In 65 cases (70%) among 93 patients with hyperthyroidism the decrease of pigmentation was observed by treatment and it was deduced that in these 65 patients the pigmentation was increased by hyperthyroidism From the study using the monochromatic lights for reflection measurement, it was concluded that this decrease of hyperpigmentation was mainly due to the decrease of melanin content of the skin. The mechanism of increase of pigmentation in hyperthyroidism was discussed.
日本内分泌学会の論文