Neuromyelitis Optica Spectrum Disorder: 2-Deoxy-2-[18F]Fluoro-D-Glucose Positron Emission Tomography Findings
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概要
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A 51-year-old female with a history of rheumatoid arthritis rapidly developed anterior neck pain and paresis in the left upper and lower extremities and right lower extremity, sensory disturbance in the left upper and lower extremities, and bladder and rectal disorder. Adduction of the left eye and abduction of the right eye were also disturbed. Spinal magnetic resonance imaging demonstrated severe edema in the C1-T5 levels, which then deteriorated rapidly over 3 days, and lesions enhanced with gadolinium in the C1-C3 and C5-T3 levels. 2-Deoxy-2-[18F]fluoro-D-glucose positron emission tomography study demonstrated the inflammatory sites as segmental enhanced accumulation in the C1-C3, C5-C6, and T1 levels. The serum anti-aquaporin 4 antibody level was positive and she was diagnosed with neuromyelitis optica spectrum disorder. Marked improvement in the neurological conditions, concomitant with reduced spinal cord edema, was obtained by steroid pulse therapy.
著者
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Noda Tomoyuki
Department Of Industrial Chemistry University Of Tokyo
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Maki Hideki
Department Of Neurosurgery Ogaki Municipal Hospital
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Oyama Hirofumi
Department Of Human Welfare Ritsumeikan University
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Kito Akira
Department Of Neurosurgery Ogaki Municipal Hospital
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Wada Kentaro
Department Of Legal Medicine Nippon Medical School
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Hattori Kenichi
Department Of Applied Physics Waseda University
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Miwa Shigeru
Department Of Neurology Ogaki Municipal Hospital
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Sobajima Atsuhiro
Department Of Medical Technology Ogaki Municipal Hospital
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WADA Kentaro
Department of Neurosurgery, Ogaki Municipal Hospital
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