Glioblastoma Detected at the Initial Stage in its Developmental Process : Case Report
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概要
- 論文の詳細を見る
A 73-year-old male presented with a glioblastoma that was detected at the initial stage in the developmental process. He suffered cerebral infarction. Follow-up magnetic resonance (MR) imaging showed no abnormality. Ten months later, he had transient right hemiparesis. Diffusion-weighted and fluid-attenuated inversion recovery (FLAIR) MR imaging showed a hyperintense area in the left frontal lobe. The diagnosis was cerebral infarction and antiplatelet drug treatment was begun. The patients right hemiparesis subsided. Ten days later, right hemiparesis reappeared. Diffusion-weighted and FLAIR MR imaging showed an enlarged hyperintense area in the left frontal lobe. Three weeks after the onset of right hemiparesis, MR imaging revealed an irregular ring-enhanced mass lesion that had further increased in size. The diagnosis was brain abscess and antibiotic treatment was initiated. However, the lesion did not respond and had further enlarged 5 weeks after the onset of right hemiparesis. The lesion was partially removed and the histological diagnosis was glioblastoma with Ki-67 labeling index of 26%. After surgical treatment, the patient received irradiation of 60 Gy and chemotherapy with temozolomide. Follow-up MR imaging showed regrowth of the tumor and aggravation of edema. The rapid progression of the tumor ultimately resulted in the patients death 12 months after the onset of right hemiparesis. Diffusion-weighted imaging is a good method for the early detection of glioblastoma.
- 2010-05-15
著者
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OYAMA Hirofumi
Department of Neurosurgery, Ogaki Municipal Hospital
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KITO Akira
Department of Neurosurgery, Ogaki Municipal Hospital
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MAKI Hideki
Department of Neurosurgery, Ogaki Municipal Hospital
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HATTORI Kenichi
Department of Neurosurgery, Ogaki Municipal Hospital
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TANAHASHI Kuniaki
Department of Neurosurgery, Ogaki Municipal Hospital
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ANDO Yusuke
Department of Neurosurgery, Ogaki Municipal Hospital
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AOKI Shinichirou
Department of Neurology, Ogaki Municipal Hospital
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Ando Yusuke
Department Of Neurosurgery Ogaki Municipal Hospital
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Ando Yusuke
Department Of Cardiovascular Surgery Fukuoka Children's Hospital
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Maki Hideki
Department Of Neurosurgery Ogaki Municipal Hospital
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Oyama Hirofumi
Department Of Neurosurgery Ogaki Municipal Hospital
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Oyama Hirofumi
Department Of Human Welfare Ritsumeikan University
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Kito Akira
Department Of Neurosurgery Ogaki Municipal Hospital
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Hattori Kenichi
Department Of Neurosurgery Ogaki Municipal Hospital
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Aoki Shinichirou
Department Of Neurology Ogaki Municipal Hospital
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Tanahashi Kuniaki
Department Of Neurosurgery Ogaki Municipal Hospital
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Hattori Kenichi
Department Of Applied Physics Waseda University
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