幼若ラット口蓋への外科的侵襲の影響についての実験的研究

概要

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In order to detect growth impairment induced after cleft palate surgery, the author conducted a study using 190 infant male rats (100g) . The right halves of all rats' palates were operated upon ; in Group A 30, the lateral half of the mucoperiosteum on right half of the palate ; in B 30, the medial half ; and, in C 30, anteriorly from the 1st mole, was stripped off to expose the bone. In D 30, the mucoperiosteum was lifted up and half of it was laterally exised and, anteriorly, from the 1st mole, excised. In E 30, the mucoperiosteum was lifted up and then replaced. And F 40 was the control. The author examined the dry bones according to the deviation of the mid-palatal suture, calculating the ratio of the area and mole to suture distance between operated rats' and non-operated rats' sides and the reduction rates with the passage of time. The results on these calculations were defined as the influence degree of the experiments. The results on Groups A, B and D were extreme, especially on Group B ; effects on Group E were slight and Groups C and F were somewhat as mucoperiosteal exposure influenced. Therefore, the author suspected that clinical exposure of the palatal bone, as well to be undermining influences on mid-palatal suture. This is especially true in the case of palatal bone exposure, suggesting that this bone exposure, at least around the mid-palatal suture, should be avoided.