頭頚部腫瘍の電顕的観察--基底膜の存在意義を中心に (内藤儁教授退官記念論文集)

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In recent years, we observed systematically the specimens of the head and neck tumors including both benign and malignant tumors.These were tumors arising from the squamous epithelium, salivary glands, neurogenic tumors, malignant lymphoma and malignant melanoma etc.Electron microscopical basal lamina (basement membrane) was observed in detail. As a result, the continuity of basal lamina could be devided into the four types. Type one is clear and continuous basal lamina. In ca. in situ, basal lamina would be continuous. Type four is complete defect of basal lamina. This type was observed only in the case of poorly differentiated carcinoma.It will be provable that the continuity of electron microscopical basal lamina relates to pathohistological malignancy. In some tumors, basal lamina is useful for recognizing their origin.Therefore, the electron microscopical observations for the head and neck tumors are proved to be a valuable diagnostic tool in surgical pathology.
耳鼻咽喉科臨床学会の論文