SO2曝露のニワトリ鼻粘膜分泌細胞に及ぼす影響 (三吉康郎教授開講20周年記念論文集)

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Acini and goblet cells of the terminal one-third of the chicken maxillary choncha during exposure to moderate levels of SO2 over time were studied histochemically. Numbers of luminal acinal cells containing intracellular glycoproteins were sharply reduced on the 1st, 7th and 14th days of 11.8ppm SO2 exposure, while goblet cell numbers were markedly increased during the exposure. Modifications of types of the intracellular glycoprotein were not observed in acinar cells. The increased goblet cells contained neutral glycoprotein predominantly on the 1st and 5th days of the exposure and then contained acid glycoprotein on the 7th and 14th days of the exposure. The modification of the intracellular glycoproteins had taken place in goblet cells within 2 days during the 5th and 7th day of the exposure.
耳鼻咽喉科臨床学会の論文