モルモット慢性CM電極法とその信頼性 (服部浩教授開講10周年記念論文集)

概要

論文の詳細を見る
Until now, it has been more difficult to maintain satisfactorily permanent electrodes for cochlear microphonic (CM) measurements in guinea pigs than in cats or rabbits. We implanted Teflon-coated electrodes on the round window of the cochlea in 40 guinea pigs, and also implanted electrodes for the recording of brain stem responses in their skulls. Using these, we recorded the auditory brain stem response (ABR) and CM potentials daily for about three months. The recorded amplitudes of the ABR and CM potentials dropped suddenly about a day after the operation, but returned to their original levels in about two weeks, and remained stable thereafter.During this initial two-week period, CM potentials and ABR were also measured by bone conduction. These ABR values remained steady, and the CM amplitudes were reduced but were larger than those measured by air conduction. These results suggest that postoperative serous exudate caused a decrease in the CM amplitudes to be measured.We found permanent electrodes for CM measurements in guinea pigs to be reliable and useful for many auditory experiments.
耳鼻咽喉科臨床学会の論文