Changes in autonomic nerve receptors in the nasal mucosa in patients with allergic rhinitis after treatment.
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Autonomic nerve receptors and histamine H1 receptors in the mucosa of the inferior nasal concha were determined by receptor binding assay in patients with allergic rhinitis, those with allergic rhinitis treated with an NSP nebulizer (NSP group), and controls with chronic sinusitis. The number of acethylchol.ine receptors was significantly higher in the patients with allergic rhinitis than in the control group and significantly lower in the NSP group than in the patients with allergic rhinitis. The numbers of α1 receptors and β receptors in the patients with allergic rhinitis were significantly lower than in the control group but similar to those in the NSP group. The number of histamine H1 receptors did not differ among the 3 groups.
- 耳鼻咽喉科臨床学会の論文
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