Clinical effect of Metharmon-F on climacterium patients with otorhinolaryngological unidentified clinical syndrome.

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The clinical effects of Metharmon®-F were evaluated in 91 patients with climacteric disorders consisting mainly of otorhinolaryngological syndrome.Metharmon®-F was administered in a dose of 2 tablet par day for 4 weeks.By global judgement, the rate of effectiveness was 53.9%.Each syndrome and the rate of effectiveness was, sensation of a foreign body in the throat (55.8%), stenosis sensation in the throat (58.3%), pressure sensation in the throat (28.6%), headache (29.4%), tinnitus (30.8%), full sense of the ears (31.3%), dizziness (50.0%), olfactory-gustatory disturbance (33.3%), abnormal sensation in oral region (33.3%).Side effects of this drug were one stomachache and one fever in one patient each, but each syndrome was slight. It was concluded that Metharmon®-F is useful in the treatment of climacteric disturbance in otorhinolaryngological region.
耳鼻咽喉科臨床学会の論文