当教室における鼻副鼻腔悪性腫瘍症例の統計的観察 (藤田学園名古屋保健衛生大学医学部耳鼻咽喉科学教室開講10周年記念論文集)

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Thirty-seven patients with malignancies in the nasal cavity and the paranasal sinus were investigated retrospectively at our institution during the period from 1973 to 1982. Our series were discussed clinically.Twenty-five patients were males and twelve females, males being predominant. Their ages ranged from 33 to 85 years. The tumors were located preferentially in the maxillary antrum (89.2%). Squamous cell carcinoma (33 cases), malignant melanoma (2 cases), adenoid cystic carcinoma (1 case), mucoepidermoid carcinoma (1 case), fibrosarcoma (1 case) and malignant hemangiopericytoma (1 case) were observed pathologically. The chief complaints were swelling of the cheek, nasal obstruction, epistaxis and neuralgia in the face. The major group of the maxillary antrum malignancy series classified by the TNM classification according to the JJC (Japanese Joint Committee) were mostly progressive cases, with 75.7% in Stage III and 21.2% in Stage IV.The prognosis of all the patients was as follows.Crude survival rate was 54.1%, three-year survival rate 38.9% and five-year survival rate 37.5%. In older and progressive cases, the prognosis tended to be poor.Local invasion of the malignant neoplasm into the brain was one of the main causes of treatment failure in our series.
耳鼻咽喉科臨床学会の論文