ヒトの扁桃および末梢血リンパ球のSubpopulationの測定--SRBCとImmunobeadsを用いたMixed Rosette Assay法による (藤田学園名古屋保健衛生大学医学部耳鼻咽喉科学教室開講10周年記念論文集)

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Lymphocyte subpopulations in the palatine tonsil, pharyngeal tonsil and peripheral blood were investigated using the mixed rosette assay with SRBC and immunobeads. Part of T-cells are counted as B cells under the conventional separate assay performed by using E or EAC rosette. However, the above method precludes such erroneous counting, and four subpopulations of lymphocytes were microscopically observed on the same field. This study showed that unlike the previous findings, tonsillar lymphocytes were not B-cell-rich. Furthermore, it was suggested that the percentages of tonsillar lymphocyte subpopulations depended greatly upon the patient's age (children or adults), or the size and condition of the tonsils. The tonsillar lymphocyte subpopulation seemed to be T-cell-rich in adult patients who had the submerged tonsils and had no recent history of tonsillitis. Similar experiments could not be conducted with children because of the absence of evidently submerged tonsils in most cases. Tonsillar lymphocytes were T-cell-rich in some patients who also had adenoids. However, this study could not clarify the type of adenoid in which the tonsillar lymphocyte population was T-cell-rich.
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