Myonal alone and in combination with other drugs in treatment of tinnitus.

概要

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Twenty-six patients consisted of 16 males and 10 females with ages ranging between 38 and 81 years, suffering from tinnitus without vertigo and hearing loss who were previously unsuccessfully treated with other drugs.They were treated with Myonal® alone and combination with kallidinogenase and minor tranzuillizer for drug therapy.The results in combination therapy were summarized as follows: in three patients (17.6%) the tinnitus was abolished entirely in a few days; improvement within 3 weeks such as abolition or marked reduction of the tinnitus was reported by eight patients (47.9%); in two patients (11.8%) the tinnitus was reduced slightly after 3 weeks or more: and no change was reported by four patients (23.5%).The treatment of Myonal® alone, however, not so effective to the tinnitus as the combined treatment: the efficacy rate with excellent and good was only 22.2%.There were no side effects in these treatment.The results of the study suggest that the clinical usefullness of Myonal is evaluated only in combined treatment with other drugs.
耳鼻咽喉科臨床学会の論文