Effects of T. T. F. D. on Auditory Fatigue, Especially its Mechanism of Effects

スポンサーリンク

概要

• 論文の詳細を見る

• Since several years the authors have been clinicaly investigating acoustic neural mechanisms. This study was designed to solve some problems on acoustic neural mechanism through effects of TTFD on neural level. As psychoacoustic method of measurement, Temporary Threshold Shift (TTS) and Temporary Auditory Summation were used in this work, and were conducted in normal ears.A series of experiments carried out before and after intra-venous administration of TTFD 50mg in this study were as follows.(1) TTS: Each TTS recovery curves after exposures to interrupted intensive tones were observed.(2) Aural Reflex: Effects of the Acoustic Reflex of the Intra-Aural Muscle on the TTS recovery curves were taken into consideration.(3) Temporary Auditory Summation: Observing the phenomena of Temporary Auditory Summation before and after intra-venous injection of TTFD, we estimated its mechanism of effects at neural level.Next results were obtained.(1) Within about 6 hours after TTFD 50mg intra-venous injection, TTS caused by high level sound exposure was decreased.(2) No change was found on Acoustic Reflex of the intra-aural muscle after TTFD injection.(3) After injection of TTFD, hearing acuity was improved temporalily. It continued for about 6 hours. The threshold was improved about 5 dB in the frequency range higher than 2000 cps. The improvement was found to be influenced by the duration of testing stimulus, and considerable improvement was obtained at 100msec duration but slight improvement at the duration shorter than 30msec.(4) As the result of psychoacoustic study, this hearing improvement could be considered as a effect of TTFD on synaptic level of acoustic neural mechanism. In order to obtain more exact findings for a affected level, more careful watches should be done. This problem will be studied in the future.

• 耳鼻咽喉科臨床学会の論文

著者

• 鰕原 勇

  東京医科歯科大学

• 辻 久茂

  東京医科歯科大学耳鼻咽喉科学教室

• 橋本 喜光

  東京医科歯科大学耳鼻咽喉科学教室

• 藤森 克男

  東京医科歯科大学耳鼻咽喉科学教室

• 平松 義郎

  東京医科歯科大学耳鼻咽喉科学教室

関連論文

• オージオメーター
• 前庭器管の基礎的研究一般演題/頭位,頭位変換眼振の診断的意義/自発眼振におよぼす前庭性,視運動性刺激の影響-その1-/自発眼振におよぼす前庭性視運動性刺激の影響-その2-/温度検査と回転検査の成績が解離した場合の診断的意義/前庭器官の基礎的研究 シンポジウム(1)[生理]/前庭器官の基礎的研究 シンポジウム(II)[形態・生化学]/前庭器官の基礎的研究 シンポジウム(III)[病態]/CPC/展示
• 純音の域値検査だけでできる感音難聴の部位診断法
• メニエール氏病を思わせたCosten氏症候群の1治験例
• 癒着性中耳炎に見られた中音域骨導の変化について
• 外耳道真珠腫症例に見られた骨導Audiogramの中音域閾値変動について
• 学童聴力測定法の研究 特に純音選別検査法について
• I.B.M.(International Business Machine)の従業員聴力及び騒音分析について
• 語音のFamiliarityの明瞭度に及ぼす影響に関する研究
• 咽喉頭神経症とSucrets口内錠療法
• 短音の聴覚現象とその聴力検査への応用
• 短音における時間的エネルギー積分現象の成立機序について
• 耳鼻咽喉科疾患とウィルス療法(矢追抗原)
• 薬の効果判定法の研究 各種ビタミンB1内服錠と「きこえ」の機能との関係を中心として
• 耳鼻咽喉科領域における0.1%Dexamethasone-21-Phosphate溶液(0.1%デカドロン液)の局所使用による治療効果について
• 補充現象の診断的意義
• アリナミンF(TTFD)内服錠の効用 特に感音機構への作用機序に関する知見補遺
• Multi-Dimensional(MD)Audiometerについて
• Effects of T. T. F. D. on Auditory Fatigue, Especially its Mechanism of Effects
• GB 105(N-phenyl-N-acetylglycine dimethylamide)注射液の耳鼻咽喉科領域における鎮痛,解熱,消炎効果について
• タイトル無し

もっと見る 閉じる

スポンサーリンク