OXIDATION PRODUCT OF THIAMINE ANHYDRIDE AND THE METABOLITE OF THIAMINE ANHYDRIDE IN RATS

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概要

• 論文の詳細を見る

• Thiamine anhydride sulfoxide (mp 131-132°) and thiamine anhydride sulfone (mp 131°) were obtained as pure crystals by oxidation of thiamine anhydyde with hydrogen peroxide. Both the compounds showed higher melting-points of 177° and 155°, respectively, after careful drying and returned to the former melting range by recrystallization. Both compounds can be distinguished either by infrared spectra or by PbO2 oxidation. The urinary metabolite of thiamine anhydride, melting at 172-173°, was proved to be thiamine anhydride sulfoxide.

• 日本ビタミン学会の論文

著者

• 富田 勲

  School of Pharmaceutical Sciences University of Shizuoka

• 富田 勲

  School of Pharmacy, Osaka University

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