BRAIN γ-AMINOBUTYRIC-α-KETOGLUTARIC TRANSAMINASE
スポンサーリンク
概要
- 論文の詳細を見る
1. When mice are raised on a vitamin B6-deficient diet, there is a decrease in activity of the enzyme involved in the transamination reaction between γ-aminobutyric acid and α-ketoglutaric acid in the brain and the activity is restored by administration of vitamin B6.2. This enzyme is inhibited by carbonyl reagents and is restored by pyridoxal phosphate. There is no increase in activity, however, in normal animal brain when pyridoxal phosphate is added.3. The activity of the enzyme is lost by dialysis and restored by addition of pyridoxal phosphate.4. Pyridoxal phosphate is considered to be involved as a coenzyme of this enzyme.
- 日本ビタミン学会の論文
著者
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KONISHI Shiro
Department of Pharmacology, Faculty of Medicine, Tokyo Medical and Dental University
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KODAMA TEISUKE
Department of Pediatrics, Faculty of Medicine, Osaka University
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NISHIZAWA YOSHITO
Department of Pediatrics, Faculty of Medicine, Osaka University
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Konishi Shiro
Department of Chemistry, Faculty of Science, Tohoku University
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KONISHI SHIRO
Department of Pediatrics, Faculty of Medicine, Osaka University
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