Experimental and clinical study of ceramic filler implantation.

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Because of our interesting in the good hitocompatibility of Al2O3 filler, as a new imimplant material, we performed an experiment on rats and rabbits to determine what kind of clinical application could be made. These results were presented at the 3rd. Orthopaedic Ceramic Implants Meeting in 1983.In this paper, we will report on 8 clinical cases counducted using results from previous experiments as a base.(Case) Eight clinical cases include 3 cases of bone cyst, 2 cases of giant cell tumor, 2 cases of benign chondroblastoma and a case of osteomyelitis. Follow up period is from 6 months to 2 years 11 months, average 1 year 5 months.(Result) From results of our experiments, we found that a ratio of 1 to 1 mixture of Al2O3 filler and autobone produced the best results when implanted to the site of bone lesion. This was the method used in our clinical cases. Radiographically, implant lesions became homogenous at 2 months to 12 months after surgery, average 4 months. These cases have no recurrence and good clinical course.
西日本整形・災害外科学会の論文