Anemia and Liver Cell Necrosis in Beagle Dogs
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概要
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Liver cell necrosis was caused in beagle dogs, whose blood in amount of one to two percent of the bodyweight was removed almost everyday for 6 weeks and their hematocrit values were approximately 10% at necropsy time. When animals are in a severe anemic condition attributable to drug administration in toxicological studies, anemia should be considered as a causative factor of liver damage in addition to the possibility of the direct effect of chemicals on the liver.
- 日本毒性病理学会の論文
日本毒性病理学会 | 論文
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