BCG生菌大量静注によつて誘導されるsuppressor adherent細胞 : II) そのsuppressor adherent細胞の性質

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概要

• 論文の詳細を見る

• In the previous report, the present author showed that the suppression by live BCG-pretreatment on delayed-type hypersensitivity is possibly mediated with adherent macrophage-like cells, by the use of the macrophage migration inhibition test.<BR>The present study was undertaken to characterize the adherent cells involved in this suppression.<BR>The result were as follows:<BR>1) The adherent cells from mice injected with live BCG at least 12 days before cell harvest showed the suppressive effect.<BR>2) The suppressive effect of the adherent cells acted beyond the major histocompatibility (H-2) barrier; it was shown both in C3H/He and C57BL/6 mice.<BR>3) The suppressive adherent cells were sensitive to methotrexate but not to cyclophosphamide.

• 日本結核病学会の論文

著者

• 加藤 一之

  北海道大学免疫科学研究所細菌感染部門

関連論文

• BCG細胞壁による肺肉芽腫形成反応における細胞性免疫の関与
• BCG生菌大量静注によつて誘導されるsuppressor adherent細胞 : II) そのsuppressor adherent細胞の性質
• BCG生菌大量静注によつて誘導されるsuppressor adherent細胞 : I) In vitroにおける遅延型反応抑制の解析

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