肺非定型抗酸菌症34例の検討
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概要
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During the past ten-year period from 1966 to 1975, 34 cases of pulmonary atypical mycobac teriosis were found at Nagahama Hospital. All of the cases were classified into three groups, Group I, II and III according to the Runyons Classification, and were further tabulated by the following categories:<BR>1. The yearly changes in the number of total cases and in each group (Table 1).<BR>2. Age and sex distribution (Table 2).<BR>3. Mode of detection (Table 3).<BR>4. Occupation and exposure to dust (Table 4, 5).<BR>5. Medical history related to the lung diseases (Table 6).<BR>6. X-ray findings of the chest (Table 7).<BR>7. The relation between course of bacilli in sputum and X-ray findings (Table 8).<BR>8. Identification of mycobacteria (Table 9). Thirty-two strains isolated from 34 patients were cultured successively and they were identified. All the strains in Group I identified as M. kansasii, those in Group II as M. scrofulaceum and those in Group III as M. intracellulare.<BR>To sum up, it is concluded as follows:<BR>a) Incidence of pulmonaly atypical mycobacteriosis has been increasing in the authors hospital. In 1975, three patients were found to be infected with M. kansasii which has been considered as less in common in Japan.<BR>b) It has been reported that infection due to M. scrofulaeum is found very frequently among patients who were exposed to dusty environment. In this study it was noted that most of the patients who were infected with M. kansasii and M. intracellulare had worked and/or lived in dusty places.<BR>c) Most of the cases of pulmonary infection due to M. intracellulare and M. scrofitlaceum showed cavities on chest radiogramme, the majority of which were found in apex. No patients showed cavities developed by the destruction of caseous masses, which are seen commonly in case of pulmonary tuberculosis.<BR>d) Most of the patients with infection due to 1V1. intracellulare showed aggravation even receiving chemotherapy with persistent bacilli discharge. As the majority of patients were aged, surgical treatments were usually not feasible to them. Therefore, it is urgently needed to develop effective drugs against M. intracellulare.
- 日本結核病学会の論文