ゲルトネル腸炎菌由来顆粒画分接種マウスの腹腔内感染像とその時間的消長

概要

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Mice immunized intraperitoneally with the particulate fraction obtained as the sediment after centrifugation at 92, 600g for 60 minutes from sonically disintegrated cells were challenged with the living cells through the same route, and the aspects of infection in the peritoneal cavity were investigated according to the lapse of time.In the analysis of cells which appeared in the peritoneal cavity after the challenge, polymorphonuclear leucocytes seemed to play a leading role. The rates of phagocytosis and inhibition of intracellular colony formation in immunized mice were higher than those of respective control animals, and the number of extracellular living cells decreased markedly also in immunized animals. These tendencies were known to commence on the 24th hour after immunization.
日本細菌学会の論文