SUBCELLULAR ASCORBIC ACID IN SCORBUTIC GUINEA PIG BRAIN
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概要
- 論文の詳細を見る
In scorbutic guinea pigs fed an ascorbic acid-deficient diet for 18 days, the ascorbic acid contents of the liver and plasma were less than 4% those of the control animals, while the content in the brain was about one-third that of the controls. In normal animals, the concentration of ascorbic acid was highest (7.55±1.46μg of ascorbic acid/mg protein) in the S3 fraction and was also fairly high (5.37±0.91) in the P2p fraction (cytoplasm of nerve terminals). During ascorbic acid deficiency, the contents in the P2p and microsome fractions decreased slightly faster than those in other fractions. Even after 18 days deficiency, no significant change was found in the acetylcholine content of the brain.
- 財団法人 学会誌刊行センターの論文
著者
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吉田 博
Department of Neuropharmacology and Neurochemistry, Institute of Higher Nervous Activity, Faculty of
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郭 哲輝
Department of Pharmacology I, Osaka University School of Medicine
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米原 典史
Department of Pharmacology I, Osaka University School of Medicine
関連論文
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- SUBCELLULAR ASCORBIC ACID IN SCORBUTIC GUINEA PIG BRAIN
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- THE UPTAKE OF CATECHOLAMINES BY SUBCELLULAR GRANULES IN THE BRAIN STEM
- INHIBITIONS BY OUABAIN AND PROTOVERATRINE ON ACTIVE TRANSPORT OF L-DOPA INTO BRAIN SLICES
- EFFECT OF RESERPINE ON SPONTANEOUS RELEASE OF NOREPINEPHRINE ACCUMULATED IN MITOCHONDRIAL FRACTION OF BRAIN STEM OF GUINEA PIG
- NORADRENALINE IN THE CAUDATE NUCLEUS OF THE RABBIT
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- STUDIES ON ACTIVE TRASPORT OF L-DOPA (DIHYDROXYPHENYLALANINE) INTO BRAIN SLICES
- MOVEMENT OF RADIOACTIVE CALCIUM IN BRAIN SLICES AND INFLUENCES ON IT OF PROTOVERATRINE, OUABAIN, POTASSIUM CHLORIDE AND COCAINE
- THE IMPORTANCE OF CALCIUM IN THE RELEASE OF CATECHOLAMINE FROM THE ADRENAL MEDULLA
- INCREASE IN DESTRUCTION OF CREATINE PHOSPHATE IN GUINEA PIG BRAIN SLICES BY OUABAIN AND THE PREVENTION OF THIS CHANGE BY COCAINE