Effect of Vitamin A Compounds on the Covalent Binding of Benzo (a) pyrene to Nuclear Macromolecules

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概要

• 論文の詳細を見る

• Effect of vitamin A compounds on the covalent binding of benzo (a) pyrene [B (a) P] to subnuclear components was studied using rat liver nuclei in vitro. The retinol-induced inhibition of the covalent binding of B (a) P depended both on the dose and the time of addition. Retinal and retinyl acetate were both potent inhibitors, but retinoic acid was less effective. Retinol induced marked inhibition of B (a) P binding to DNA and protein of the nuclear matrix but had little or no effect on the labeling of bulk DNA and protein in chromatin fractions.

• 財団法人 学会誌刊行センターの論文

著者

• 能見 伸八郎

  滋賀医大生化学第2

• 能見 伸八郎

  Department of Medical Biochemistry, Shiga University of Medical Science

• 松浦 尚雄

  Department of Medical Biochemistry, Shiga University of Medical Science

• 上山 久雄

  Department of Medical Biochemistry, Shiga University of Medical Science

• 上田 潔

  Department of Medical Biochemistry, Shiga University of Medical Science

• 上山 久雄

  Department o f Medical Biochemistry, Shiga University of Medical Science

• 松浦 尚雄

  Department of Biochemistry, Kyoto Prefectural University of Medicine

• 上田 潔

  Department o f Medical Biochemistry, Shiga University of Medical Science

• 能見 伸八郎

  Department o f Medical Biochemistry, Shiga University of Medical Science

• 松浦 尚雄

  Department o f Medical Biochemistry, Shiga University of Medical Science

関連論文

• 細胞核内高分子物質へのベンツピレン代謝物の結合に及ぼすビタミンAの影響 : 日本ビタミン学会第32回大会一般研究発表要旨
• ベンツピレンの細胞核内代謝に及ぼすα-Tocopherolの影響 : 日本ビタミン学会第31回大会研究発表要旨
• Effect of Vitamin A Compounds on the Covalent Binding of Benzo (a) pyrene to Nuclear Macromolecules
• Occurrence of NADH-Diaphorases in Isolated Thymus Nuclei
• Effect of .ALPHA.-tocopherol on the binding of benzo(a)pyrene to nuclear macromolecules.
• Detection of reaction products of thiamin degradation by catechol derivatives.
• Isolation and characterization of a coupled compound of thiamin with catechol.

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