Effects of low protein intake on protein metabolism of Papua New Guinea highlanders studied with (15N)glycine.

概要

論文の詳細を見る
The effects of low protein intake on protein metabolism, including the size of pools and the protein synthesis rates, were studied by use of [15N] glycine in Papua New Guinea highlanders. Studies were made on 9 men between October and December in 1982. In experiment 1, two subjects were given a protein-free diet (PFD) containing 49.1 kcal/kg of energy. In experiment 2, subjects were given a sweet-potato diet (SPD) containing 45.4kcal/kg of energy and 0.507g/kg of protein for 8 days, and then were given a low-protein sweet-potato diet (LPSPD) containing 50.0 kcal/.kg of energy and 0.265g/kg of protein. During the SPD period, the sizes of the metabolic and active protein pools (mean±SD) were 270±134mgN/kg and 362±107mgN/kg, respectively, and the rates of active and inactive protein synthesis were 463±161 mgN/kg/day and 299±38mgN/kg/day, respectively. During the LPSPD period, the sizes of the metabolic pool and active protein pool were 131±64 mgN/kg and 378±106mgN/kg, respectively, and the rates of active and inactive protein synthesis were 490±206mgN/kg/day and 280±26mgN/kg/day, respectively. The protein metabolism in the LPSPD showed no significant difference from the SPD. The results suggest that, when the energy levels were approximately the same, protein metabolism in Papua New Guinea highlanders was maintained in spite of the decrease in protein intake.
財団法人学会誌刊行センターの論文