Formation of a biotin precursor, pimelic acid, in yeasts from C18 fatty acids.

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概要

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• The biosynthesis of biotin-vitamers from C18 fatty acids in the resting cell reaction system of yeasts was investigated. The formation of pimelic acid (a biotin precursor) and biotin-vitamers (a mixture of 7-keto-8-aminopelargonic acid and dethiobiotin) from linolenic, linoleic, and oleic acids was observed in certain yeasts belonging to the genera Cryptococcus, Candida, Rhodotorula, and Trichosporon. Metabolites from linolenic acid were analyzed by gas-liquid chromatography and mass spectrometry. Linoleic, oleic, stearic, heptadecanoic, palmitic, penta-decanoic, and pimelic acids were identified as metabolites of linolenic acid. The existence of a route to pimelic acid from linolenic acid in a strain of Rhodotorula rubra AKU 4836 was also indicated.

• 財団法人 学会誌刊行センターの論文

著者

• 中尾 祥子

  Laboratory of Food Microbiology, Department of Food Science, Faculty of Home Economics, Mukogawa Women's University

関連論文

• Effects of the Yeast Extract Components Pyrroloquinoline Quinone and Aspartic Acid on Vitamin B12 Production in Klebsiella pneumoniae IFO 13541
• Biosynthesis of biotin-vitamers by family enterobacteriaceae.
• Formation of a biotin precursor, pimelic acid, in yeasts from C18 fatty acids.

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