Microencapsulated Ferrous Sulfate to Fortify Cow Milk: Absorption and Distribution in Mice.
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概要
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To determine the absorption and biodistribution of iron from microencapsulated ferrous sulfate (SFE-171), used to fortify dairy products with iron, a comparative study in four groups of 30 mice each was carried out. In two of the groups, the absorption of iron from ferrous ascorbate in water (13.3±4.3%) and from ferrous sulfate in water (12.7±3.9%) was determined and taken as reference standards. In the third group the iron absorption from SFE-171 in milk was determined, giving a value of 12.1±4.2%, which statistically does not differ from the data obtained with either reference standard. In the fourth group, the absorption of iron from ferrous sulfate in milk showed a value of 7.7±3.4%, which statistically differs with a p<0.01 from the data corresponding to the other three groups. The biodistribution studies showed that the iron from SFE-171 follows the same metabolic pathway as the iron from the reference standards thus, giving a higher radioac-tivity percentage and radioactivity concentration in organs or systems, principally blood, that are closely related to iron metabolism. Our studies allow us to conclude that the iron from SFE-171 in milk follows the same behavior as the nonhemic iron, with a higher absorption than that of ferrous sulfate in milk.
- 財団法人 学会誌刊行センターの論文
著者
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LYSIONEK Alexis
Radioisotope Laboratory, School of Pharmacy and Biochemistry, University of Buenos Aires
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ZUBILLAGA Marcela
Radioisotope Laboratory, School of Pharmacy and Biochemistry, University of Buenos Aires
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SALGUEIRO Maria
Radioisotope Laboratory, School of Pharmacy and Biochemistry, University of Buenos Aires
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SARABIA Maria
Radioisotope Laboratory, School of Pharmacy and Biochemistry, University of Buenos Aires
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CARO Ricardo
Radioisotope Laboratory, School of Pharmacy and Biochemistry, University of Buenos Aires
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BOCCIO Jose
Radioisotope Laboratory, School of Pharmacy and Biochemistry, University of Buenos Aires
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CALMANOVICI Gabriela
Radioisotope Laboratory, Physics Department, School of Pharmacy and Biochemistry, University of Buenos Aires
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WEILL Ricardo
Center of Research and Development, La Serenísima, Buenos Aires
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SALGUEIRO María
Radioisotope Laboratory, Physics Department, School of Pharmacy and Biochemistry, University of Buenos Aires
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WEILL Ricardo
Center of Research and Development, La Serenísima, Buenos Aires
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CARO Ricardo
Radioisotope Laboratory, Physics Department, School of Pharmacy and Biochemistry, University of Buenos Aires
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LYSIONEK Alexis
Radioisotope Laboratory, Physics Department, School of Pharmacy and Biochemistry, University of Buenos Aires
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BOCCIO Jose
Radioisotope Laboratory, Physics Department, School of Pharmacy and Biochemistry, University of Buenos Aires
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ZUBILLAGA Marcela
Radioisotope Laboratory, Physics Department, School of Pharmacy and Biochemistry, University of Buenos Aires
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ZUBILLAGA Marcela
Radioisotope Laboratory, Physics Department, School of Pharmacy and Biochemistry University
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WEILL Ricardo
Center of Research and Development
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CARO Ricardo
Radioisotope Laboratory, Physics Department, School of Pharmacy and Biochemistry University
関連論文
- Study of Industrial Microencapsulated Ferrous Sulfate by Means of the Prophylactic-preventive Method o Determine Its Bioavailability
- Bioavailability of Petit-Suisse Cheese as Food Vehicle for Iron Fortification Estimated by the Prophylactic Method
- Microencapsulated Ferrous Sulfate to Fortify Cow Milk: Absorption and Distribution in Mice.
- Bioavailability and Stability of Microencapsulated Ferrous Sulfate in Fluid Milk: Studies in Mice.
- New Procedure to Fortify Fluid Milk and Derivatives with Iron: A Comparative Study in Mice.