Bioavailability and Stability of Microencapsulated Ferrous Sulfate in Fluid Milk: Studies in Mice.

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概要

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• Iron deficiency is the most important nutritional problem all over the world. Fluid milk is an attractive vehicle for iron fortification, since it is a food with a high nutritional value, accessible to the whole population and easy to be given to children. Fortification of this food with iron has the disadvantage of the interaction of the iron with the constitutive elements of milk, diminishing its bioavailability and changing its sensorial properties, making it unacceptable. Nowadays, this problem can be overcome by the implementation of a new technological procedure, which consists in the microencapsulation of the ferrous sulfate with lecithin, thus avoiding the interaction of iron with the food. The absorption obtained in mice for milk-ferrous sulfate was 7.9±3.2%, while for microencapsulated ferrous sulfate-milk the result was 11.6±4.5%. Comparing these data with those obtained with the ferrous ascorbate in water 13.1±4, 9% and ferrous sulfate in water 13.2±4.3%, both of them considered as reference standards, no statistically significant difference between them and the microencapsulated ferrous sulfate in milk can be observed. However, this difference becomes significant (p<0.01) when these products are compared to the non-encapsulated ferrous sulfate in milk. Rn the other hand, we demonstrated that this product is stable to heat-processing (100°C, 30min) and storage at a room temperature up to 6 months that lacteous products are usually submitted to.

• 財団法人 学会誌刊行センターの論文

著者

• ZUBILLAGA Marcela

  Radioisotope Laboratory, School of Pharmacy and Biochemistry, University of Buenos Aires

• CARO Ricardo

  Radioisotope Laboratory, School of Pharmacy and Biochemistry, University of Buenos Aires

• BOCCIO Jose

  Radioisotope Laboratory, School of Pharmacy and Biochemistry, University of Buenos Aires

• WEILL Ricardo

  Center of Research and Development, La Serenísima, Buenos Aires

• GOTELLI Carlos

  Center of Toxicological Research, Buenos Aires, Argentina

• GOTELLI Mariano

  Center of Toxicological Research, Buenos Aires, Argentina

• WEILL Ricardo

  Center of Research and Development, La Serenísima, Buenos Aires

• WEILL Ricardo

  Center of Research and Development, La Serenisima, Buenos Aires, Argentina

• CARO Ricardo

  Radioisotope Laboratory, Physics Department, School of Pharmacy and Biochemistry, University of Buenos Aires

• BOCCIO Jose

  Radioisotope Laboratory, Physics Department, School of Pharmacy and Biochemistry, University of Buenos Aires

• ZUBILLAGA Marcela

  Radioisotope Laboratory, Physics Department, School of Pharmacy and Biochemistry, University of Buenos Aires

• ZUBILLAGA Marcela

  Radioisotope Laboratory, Physics Department, School of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina

• ZUBILLAGA Marcela

  Radioisotope Laboratory, Physics Department, School of Pharmacy and Biochemistry University

• WEILL Ricardo

  Center of Research and Development

• CARO Ricardo

  Radioisotope Laboratory, Physics Department, School of Pharmacy and Biochemistry University

• GOTELLI Mariano

  Center of Toxicological Research

関連論文

• Study of Industrial Microencapsulated Ferrous Sulfate by Means of the Prophylactic-preventive Method o Determine Its Bioavailability
• Bioavailability of Petit-Suisse Cheese as Food Vehicle for Iron Fortification Estimated by the Prophylactic Method
• Microencapsulated Ferrous Sulfate to Fortify Cow Milk: Absorption and Distribution in Mice.
• Bioavailability and Stability of Microencapsulated Ferrous Sulfate in Fluid Milk: Studies in Mice.
• New Procedure to Fortify Fluid Milk and Derivatives with Iron: A Comparative Study in Mice.

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