Effect of Cysteine on Expression of Cystathionine .BETA.-Synthase in the Rat Liver.

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概要

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• Hepatic cystathionine β-synthase activity is decreased by the addition of cysteine to the diet. This effect of cysteine was slightly greater in diets containing 0.25% methionine than in those containing 1 % methionine, and was reduced during aging. Similar changes were ob-served in the level of the mRNA of this enzyme, although the changes in the trancscript levels were slightly greater than the changes in enzyme activity. Thus, we conclude that the addition of cysteine to a methionine-containing diet causes a decrease in cystathionine Q-synthase activity mainly by diminishing its mRNA level.

• 財団法人 学会誌刊行センターの論文

著者

• Tanaka Takehiko

  Department Of Anatomy Osaka Dental University

• Noguchi Tamio

  Department Of Applied Molecular Biosciences Nagoya University Graduate School Of Bioagricultural Sci

• TANAKA Takehiko

  Department of Nutrition and Physiological Chemistry, Osaka University Medical School

• Yamamoto Nobuko

  Fukuokajogakuin Junior College

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