A case of malignant fibrous histiocytoma of the right maxilla - 1: Case report.:1: Case report

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Malignant fibrous histiocytoma (MFH) is defined as a neoplasm that is composed of histiocytic and fibroblastic cells. This tumor is the most common soft tissue sarcoma of late adult life with poor prognosis. The majority of tumors occur on extremities, abdomen and the retroperitoneum but uncommonly in the maxillofacial region.<BR>A case of MFH arising in the right maxilla was described. The patient, a 60-year-old female, who had swelling of the 76| alveolar part, was referred to our department by a dentist. In the first operation, A multinodular, white and grayish, tumor developing in the right maxillary sinus was noted. Up to date of writing the local recurrence was repeated, so total maxillectomie and orbital exenteration were performed. Radiotherrapy and chemotherapy as adjunctive treatment were added, the former showed good effect but the latter was ineffective. Histological findings showed histiocytic and fibroblastic cells with more pronounced nuclear atypia with a little part of storiform area. The pleomorphic giant cell and mitosis were also seen. Histochemically, the cells were positive for both acid phosphatase and naphtol AS-D acetate esterase. Histological classification of this case was the pleomorphic subtype according to Enjoji et al. The metastatic lesion at the left lung was recongnized but it was controled by radiotherapy. Primary lesion showed no sign of recurrence and this patient is being seen in the outpatient clinic wearing maxillofacial prosthetics.<BR>Although MFH of the maxillofacial region is being reported with increasing frequence, the diagnosis and treatment of this tumor must be done carefully.
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A case of malignant fibrous histiocytoma of the right maxilla - 1: Case report.:1: Case report

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