低出力レーザー照射のラット坐骨神経に及ぼす影響

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The effect of low power laser irradiation on rat sciatic nerve was examined. Kept wet with saline, the sciatic nerves were exposed unilaterally, and irradiated by CO2 laser (12J/cm2, 24J/cm2), directly. All the time, the electrophysiological changes of evoked nerve action potential were observed. Immediately after CO2 laser irradiation, nerve conduction accelerated (12J/cm2), and suppressed (24J/cm2). The temperature in the nerve rose to about 45°C (24J/cm2), and nerve conduction was blocked (>24 J/cm2). So the process of nerve regeneration was examined by compared two methods, i. e., the crush of 1 mm in length and the end to end suture after transection. In the result, the regeneration of laser irradiation group was faster than the others. And the main effect of low power CO2 laser seemed to be the heat effect. In addition, the effects of Ga-Al-As diode laser and He-Ne laser irradiation on rat sciatic nerves were observed. No clear change in nerve conduction could be observed after irradiation.
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