下顎前歯部に発生した歯原性粘液腫の1例

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A case of odontogenic myxoma of the mandible is reported. A 52-year-old woman was referred with painless swelling in the anterior portion of the mandible. The swelling had been present for 15 years and enlarged gradually. On examination, there was firm swelling in the anterior tooth region and both labial and lingual expansion of the lower alveolus were noted. X-ray films showed a well-defined intra-bony multilobular radiolucency. The biopsy suggested odontogenic myxoma. Under endotracheal anesthesia, partial resection of the mandibule was performed by an intra-oral approach. The tumor was a solid yellow white mass and showed myxomatous appearance. The bone defect was immediately reconstructed with HAP particules (Actceram K<SUP>®</SUP>), HAP-TCP block and autogenous iliac cancelous bone. In histological examination the specimen showed loosely arranged, spindlesaped and stellate cells with fine collagen fibers. There were odontogenic epitherial cell nests and a small number of calcified materials like cementicle. From these findings, the lesion was diagnosed as odontogenic myxoma. The patient was observed two years later and there was no evidence of recurrence.