エナメル上皮腫にきわめて類似した組織像を呈した顎下部腫瘤の1例

概要

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An unusual case is presented of ameloblastoma arising in the submandibular region.<BR>A 50-year-old, Japanese woman. Complained of a movable, nontender mass, approximately 40 mm in diameter, in her right submandibular region. The onset of this lesion was at age 18. During the past 32 years fluid contained in this lesion occasionally was aspirated by puncture needle as treatment.<BR>Histopathology of this lesion revealed multilocular cystic tumor showing Ishikawas Type RE ameloblastoma-like parenchyma with fibrous stroma in the lymph node. These findingssuggested that the lesion was metastatic ameloblastoma, i. e., especially malignant ameloblastoma. However, careful clinical examination failed to find the presence of the primary tumors, such as ameloblastoma of the jaw, basal cell carcinoma, squamous cell carcinoma, and craniopharyngioma.<BR>The differential diagnosis and pathogenesis of this lesion was discussed.