口腔および皮膚にみられたカポシ肉腫の1例

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A case of oral and dermis Kaposis sarcoma was reported. A 59-year-old woman had nodules on the mouth floor, the groin surface, and median surfaces of thigh and right chest. Histopathological examination of the nodules revealed proliferation of endothelium-like cell and fibroblast-like cells with extravasation of red cells and deposition of hemosiderin in the dermis. Resected tumor tissue of oral cavity was 45mm×25mm in size. Macroscopic appearance was coarse irregular surface with several ulcerations.<BR>Treatment with resection and immunotherapy (ok-432) in combination with chemotherapy (vinblastin, endoxan, predonine) was not effective for Kaposis sarcoma. She died of intestinal bleeding due to thormbocytopenia and respiratory failure.