放射線療法が奏効した前腕の類上皮肉腫の1例―前腕に発生した類上皮肉腫の1例―

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A case of epitherioid sarcoma treated with radiation was reported. A 66-year-old man with a 19×14cm tumor on his right forearm visited our hospital. A biopsy from the tumor region showed epithelioid sarcoma. MRI of his forearm showed that the tumor invaded muscles and periosteum of radius. CT showed multiple metastasis of the lung. Therefore, surgical treatment including amputation was not indicated. The tumor or metastatic region did not decrease, though the patient underwent chemothe-rapy with IFOVA (ADR, VCR and IFO) . Radiation therapy (total 3500rad.) to his forearm region was done. After the radiation therapy, the tumor mass decreased remarkably and no tumor cell was observed in the histopathological specimen. MRI of his forearm showed no abnormal sign. However, tumor metastasis was still seen in his chest CT.Discussion: Epithelioid sarcoma usually occures in the soft tissues of young adults, particularly involving the hands and forearms. In Enzingers report, there was a 10% incidence of regional lymphnode involvement, a 85% incidence of local recurrence and an over 25% incidence of distant metastasis. Chemotherapy or radiation therapy have never been employed in this tumor. However, this patient underwent radiation therapy and his tumor decreased dramatically. Histopathological specimen harvested from tumor origin, after radiation therapy, never showed abnormal cells.In conclusion, we experienced a case of epithelioid sarcoma who got decrease of tumor with radiation therapy.

放射線療法が奏効した前腕の類上皮肉腫の1例―前腕に発生した類上皮肉腫の1例―

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